Vascular Endothelial Growth Factor Receptors

A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.

Also Known As:

VEGF Receptors; Vascular Endothelial Growth Factor Receptor; Receptors, Vascular Endothelial Growth Factor; Endothelial Growth Factor Receptor; Receptor, Endothelial Growth Factors; Receptor, Vascular Endothelial Cell Growth Factor; Receptor, Vascular Permeability Factor; VEGF Receptor; VPF Receptor; Vascular Endothelial Cell Growth Factor Receptor; Vascular Permeability Factor Receptor; Receptors, VEGF

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Receptor Protein-Tyrosine Kinases: 5999
        Vascular Endothelial Growth Factor Receptors: 3385
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Receptor Protein-Tyrosine Kinases: 5999
        Vascular Endothelial Growth Factor Receptors: 3385
      - Peptide Receptors: 1159
        Growth Factor Receptors: 2663
        Vascular Endothelial Growth Factor Receptors: 3385
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Receptor Protein-Tyrosine Kinases: 5999
        Vascular Endothelial Growth Factor Receptors: 3385

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